{"id":7091,"date":"2011-03-23T00:33:50","date_gmt":"2011-03-22T16:33:50","guid":{"rendered":"http:\/\/www.dadicdk.com\/2011\/03\/23\/%e5%81%a5%e5%ba%b7-72\/"},"modified":"2011-03-23T00:33:50","modified_gmt":"2011-03-22T16:33:50","slug":"%e5%81%a5%e5%ba%b7-72","status":"publish","type":"post","link":"http:\/\/www.dadicdk.com\/?p=7091","title":{"rendered":"\u62a2\u6551\u4eba\u7684\u8bb0\u5fc6(\u963f\u5179\u6d77\u9ed8\u75c7)&#8207;"},"content":{"rendered":"<p><TABLE border=0 cellPadding=0 width=\"100%\"><br \/>\n<TBODY><br \/>\n<TR><br \/>\n<TD><br \/>\n<P align=left>\u89e3\u5f00\u767e\u5e74\u8c1c\u56e2\u3000\u62a2\u65512,600\u4e07\u4eba\u7684\u8bb0\u5fc6 <\/P><br \/>\n<P align=left><B>\u300c\u90a3\u5929\uff0c\u5916\u5a46\u5fd8\u4e86\u56de\u5bb6\u7684\u8def\u300d\u4e0d\u754f\u8270\u96be\uff0c\u53ea\u56e0\u5979\u5fd8\u4e0d\u4e86\u90a3\u5931\u843d\u7684\u8138<\/B><\/P><br \/>\n<P align=left>&nbsp;<\/P><br \/>\n<P align=left>\u4e3a\u4f55\u80fd\u5bf9\u7814\u7a76\u8bb0\u5fc6\u8fd9\u4ef6\u4e8b\u60c5\uff0c\u6267\u7740\u81f3\u6b64\uff1f\u5979\u600e\u4e48\u4f1a\u76f8\u4fe1\uff0c\u81ea\u5df1\u5c31\u80fd\u89e3\u5f00\u8fd9\u4e2a\u5343\u5e74\u6765\u6ca1\u4eba\u89e3\u5f00\u7684\u8c1c\u56e2\uff1f\u597d\u5f3a\u7684\u8521\u7acb\u6167\uff0c\u6700\u540e\u8bf4\u4e86\u4e00\u4e2a\u5f88\u67d4\u8f6f\u7684\u6545\u4e8b\u3002<\/P><br \/>\n<P align=left>\u300c\u90a3\u65f6\u5019\u6211\u624d\u4e09\u5c81\u3002\u6211\u4e00\u51fa\u751f\uff0c\u6211\u7238\u5988\u5c31\u8ba9\u6211\u4f4f\u5728\u57fa\u9686\uff0c\u8ddf\u5916\u5a46\u4e00\u8d77\u4f4f\u3002<\/P><br \/>\n<P align=left>\u5979\u4f1a\u5e26\u6211\u53bb\u83dc\u5e02\u573a\uff0c\u4e70\u83dc\u554a\uff0c\u4e00\u8d77\u5403\u9762\uff0c\u7136\u540e\u6709\u65f6\u5019\u4f1a\u5750\u516c\u4ea4\u8f66\u3001\u53bb\u533b\u9662\u3002<\/P><br \/>\n<P align=left>\u7ed3\u679c\u90a3\u4e00\u5929\uff0c\u7ad9\u5728\u9a6c\u8def\u4e0a\uff0c\u5979\u5ffd\u7136\u770b\u7740\u6211\uff0c\u7136\u540e\u95ee\u6211\uff0c\u6211\u4eec\u8be5\u600e\u4e48\u56de\u5bb6\uff1f\u300d<\/P><br \/>\n<P align=left>\u300c\u90a3\u4e2a\u8868\u60c5\uff0c\u5230\u73b0\u5728\u6211\u8fd8\u8bb0\u5f97\u2026\u2026\uff08\u505c\u987f\u4e00\u4e0b\uff09\uff0c\u5c31\u662f\u5f88\u5931\u843d\uff0c\u6211\u77e5\u9053\u5979\u662f\u771f\u7684\u4e0d\u8ba4\u5f97\uff0c\u771f\u7684\u4e0d\u8ba4\u5f97\uff0c\u6700\u540e\uff0c\u662f\u6211\u7275\u7740\u5979\u56de\u5bb6\u7684\uff0c\u300d\u300c\u5230\u540e\u6765\uff0c\u6211\u4eec\u624d\u77e5\u9053\uff0c\u90a3\u5c31\u662f\u963f\u5179\u6d77\u9ed8\u75c7\u2026\u2026\u3002\u300d<\/P><br \/>\n<P align=left>\u300c\u6211\u4e00\u76f4\u4ee5\u4e3a\u6211\u5fd8\u6389\u4e86\uff0c\u4f46\uff0c\u5176\u5b9e\u6ca1\u6709\u3002\u300d\u6bcf\u5f53\u8521\u7acb\u6167\u7814\u7a76\u9047\u5230\u74f6\u9888\u4e0e\u632b\u6298\u65f6\uff0c\u5979\u5e38\u5e38\u4f1a\u60f3\u5230\uff0c\u90a3\u65f6\u5916\u5a46\u7684\u8868\u60c5\u3002<\/P><br \/>\n<P align=left>\u5c31\u8fd9\u6837\uff0c\u56db\u5341\u4e94\u5e74\u524d\u4e00\u4e2a\u4f24\u75db\u7684\u8bb0\u5fc6\uff0c\u88ab\u5f53\u5e74\u7684\u5c0f\u5973\u5b69\u5316\u4e3a\u529b\u91cf\u3002<\/P><br \/>\n<P align=left>\u5979\u65e0\u6cd5\u66ff\u5df2\u7ecf\u53bb\u4e16\u7684\u5916\u5a46\u627e\u56de\u8bb0\u5fc6\uff0c\u4f46\u53ea\u8981\u518d\u52aa\u529b\u70b9\u3001\u66f4\u575a\u5f3a\u70b9\uff0c<\/P><br \/>\n<P align=left>\u6216\u8bb8\u6709\u4e00\u5929\uff0c\u5c31\u80fd\u66ff\u4e24\u5343\u591a\u4e07\u4eba\uff0c\u628a\u6682\u65f6\u6309\u4e0a\u300coff\uff08\u5173\u95ed\uff09\u300d\u7684\u8bb0\u5fc6\u5f00\u5173\uff0c\u91cd\u65b0\u6253\u5f00\u6765\u3002<\/P><br \/>\n<P align=left><BR><A href=\"http:\/\/www.businessweekly.com.tw\/mag.php?id+12\" target=_blank><B>\u5546\u4e1a\u5468\u520a\u7b2c<\/B><B>1087<\/B><B>\u671f<\/B><\/A><B> <\/B><B>2008-09-22<\/B><B>&nbsp;<\/B> <BR>&nbsp;&nbsp;&nbsp;&nbsp;<\/P><br \/>\n<P align=left><B>\u6700\u9ad8\u7968\u4e2d\u7814\u9662\u65b0\u9662\u58eb\u8521\u7acb\u6167\uff0c\u627e\u5230\u63a7\u5236\u5931\u667a\u7684\u5f00\u5173<\/B><\/P><br \/>\n<P align=left>&nbsp;<\/P><br \/>\n<P align=left>\u8521\u7acb\u6167\uff0c\u7f8e\u56fd\u9ebb\u7701\u7406\u5de5\u5b66\u9662\u5927\u8111\u4e0e\u8ba4\u77e5\u79d1\u5b66\u7cfb\u6559\u6388\uff0c\u9760\u7740\u963f\u5179\u6d77\u9ed8\u75c7\u7684\u7814\u7a76\uff0c\u6210\u4e3a\u4eca\u5e74\u4e2d\u7814\u9662\u9662\u58eb\u9009\u4e3e\u4e2d\uff0c\u6700\u9ad8\u7968\u4e0e\u6700\u5e74\u8f7b\u7684\u5973\u9662\u58eb\u3002 <\/P><br \/>\n<P align=left>&nbsp;<\/P><br \/>\n<P align=left>\u4f60\u6709\u6ca1\u6709\u60f3\u8fc7\uff0c\u6709\u4e00\u5929\uff0c\u4f60\u4f1a\u7ad9\u5728\u5341\u5b57\u8def\u53e3\uff0c\u5374\u627e\u4e0d\u5230\u56de\u5bb6\u7684\u8def\u3002\u4f60\u770b\u7740\u6700\u7231\u7684\u4eba\uff0c\u5374\u518d\u4e5f\u60f3\u4e0d\u8d77\u4ed6\u7684\u540d\u5b57\uff1f<\/P><br \/>\n<P align=left>&nbsp;<\/P><br \/>\n<P align=left>\u8fd9\u662f\u963f\u5179\u6d77\u9ed8\u75c7\uff08Alzheimer&#8217;s disease\uff09\uff0c\u4e5f\u5c31\u662f\u4fd7\u79f0\u8001\u5e74\u5931\u667a\u75c7\u3001\u8001\u5e74\u75f4\u5446\u75c7\u7684\u6807\u51c6\u75c5\u5f81\u3002\u5728\u5168\u7403\uff0c\u5df2\u6709\u4e8c\u5343\u516d\u767e\u4e07\u4eba\u5f97\u5230\u6b64\u75c5\u3002<\/P><br \/>\n<P align=left>\u8d85\u8fc7\u516d\u5341\u4e94\u5c81\u8005\uff0c\u7f79\u60a3\u6b64\u75c5\u7684\u6bd4\u7387\u7ea6\u4e94\uff05\u5230\u4e00\u25cb\uff05\uff1b\u8d85\u8fc7\u516b\u5341\u4e94\u5c81\u8005\u60a3\u75c5\u673a\u7387\u5219\u9ad8\u8fbe\u4e94\u25cb\uff05\u3002<\/P><br \/>\n<P align=left>&nbsp;<\/P><br \/>\n<P align=left>\u53ef\u6015\u7684\u662f\uff0c\u8fd9\u4e2a\u5df2\u7ecf\u5b58\u5728\u4eba\u7c7b\u5386\u53f2\u8d85\u8fc7\u4e00\u767e\u5e74\u7684\u75c5\u75c7\uff0c\u81f3\u4eca\uff0c\u627e\u4e0d\u51fa\u786e\u5207\u75c5\u56e0\u3001\u65e0\u836f\u53ef\u533b\uff0c\u9051\u8bba\u9884\u9632\u3002<\/P><br \/>\n<P align=left>\u5373\u4fbf\u7f8e\u56fd\u524d\u603b\u7edf\u91cc\u6839\u4e0e\u82f1\u56fd\u524d\u9996\u76f8\u6492\u5207\u5c14\u592b\u4eba\uff0c\u9762\u4e34\u963f\u5179\u6d77\u9ed8\u75c7\u65f6\uff0c\u4e5f\u53ea\u80fd\u773c\u7741\u7741\u7684\u8ba9\u75c5\u9b54\uff0c\u5c06\u4ed6\u4eec\u8111\u888b\u91cc\u7684\u8bb0\u5fc6\uff0c\u65e0\u60c5\u7684\u5543\u98df\u3002<\/P><br \/>\n<P align=left>\u300c\u81f3\u4eca\uff0c\u5927\u5bb6\u90fd\u4ecd\u50cf\u662f\u5728\u9ed1\u6697\u4e2d\u6478\u7d22\u6cbb\u7597\u7684\u65b9\u5f0f\uff0c\u300d\u53f0\u5927\u533b\u9662\u795e\u7ecf\u90e8\u4e3b\u6cbb\u533b\u5e08\u90b1\u94ed\u7ae0\u8bf4\u3002<\/P><br \/>\n<P align=left>\u300c\u4f46\u5979\u7684\u7814\u7a76\uff0c\u7ed9\u4e86\u5927\u5bb6\u4e00\u9053\u66d9\u5149\uff0c\u300d\u4e2d\u7814\u9662\u7814\u7a76\u5458\u6c88\u54f2\u9cb2\u535a\u58eb\u8bf4\u3002<\/P><br \/>\n<P align=left>\u5979\uff0c\u5c31\u662f\u8521\u7acb\u6167\uff0c\u7f8e\u56fd\u9ebb\u7701\u7406\u5de5\u5b66\u9662\u5927\u8111\u4e0e\u8ba4\u77e5\u79d1\u5b66\u7cfb\u6559\u6388\uff0c\u9760\u7740\u963f\u5179\u6d77\u9ed8\u75c7\u7684\u7814\u7a76\uff0c\u6210\u4e3a\u4eca\u5e74\u4e2d\u7814\u9662\u9662\u58eb\u9009\u4e3e\u4e2d\uff0c\u6700\u9ad8\u7968\u4e0e\u6700\u5e74\u8f7b\u7684\u5973\u9662\u58eb\u3002<\/P><br \/>\n<P align=left>\u5979\u7684\u7814\u7a76\uff0c\u8ba9\u8457\u540d\u79d1\u5b66\u671f\u520a\u300a\u81ea\u7136\u300b\uff08Nature\uff09\u4e0e\u300a\u79d1\u5b66\u300b\uff08Science\uff09\u5927\u91cf\u520a\u8f7d\u3002<\/P><br \/>\n<P align=left>\u8fc7\u53bb\uff0c\u6709\u5173\u963f\u5179\u6d77\u9ed8\u75c7\u7684\u75c5\u56e0\u7814\u7a76\uff0c\u591a\u53ea\u505c\u7559\u5728\u8111\u4e2d\u300c\u8001\u4eba\u6591\u300d\u7684\u5f62\u6210\u4e0a\uff0c\u4f46\u662f\u8521\u7acb\u6167\u5374\u627e\u5230\u4e86\u53e6\u4e00\u4e2a\u53ef\u80fd\u7684\u75c5\u56e0\u3002<\/P><br \/>\n<P align=left>\u5f53\u5927\u5bb6\u90fd\u4ee5\u4e3a\uff0c\u4e00\u65e6\u4eba\u60a3\u75c5\u4e4b\u540e\uff0c\u8bb0\u5fc6\u4e00\u65e6\u6d88\u5931\uff0c\u5c31\u4e0d\u4f1a\u518d\u56de\u6765\uff0c\u8521\u7acb\u6167\u5374\u63d0\u51fa\u4e86\uff0c\u8bb0\u5fc6\u53ef\u80fd\u518d\u6062\u590d\u7684\u8bc1\u636e\uff0c\u4e5f\u5c31\u662f\uff0c\u963f\u5179\u6d77\u9ed8\u75c7\u662f\u53ef\u80fd\u88ab\u6cbb\u6108\u7684\u3002<\/P><br \/>\n<P align=left>\u300c\u6211\u5c31\u662fambitious\uff08\u91ce\u5fc3\uff0c\u96c4\u5fc3\u58ee\u5fd7\uff09\uff0c\u4f60\u4e5f\u53ef\u4ee5\u8bf4\u5f88tough\uff08\u5f3a\u97e7\uff09\u3002\u300d<\/P><br \/>\n<P align=left>\u5916\u8868\u770b\u6765\u6e29\u67d4\u7684\u8521\u7acb\u6167\uff0c\u5728\u8d8a\u6d0b\u7535\u8bdd\u91cc\u8fd9\u6837\u5f62\u5bb9\u5979\u81ea\u5df1\u3002\u5979\u6ca1\u6709\u5938\u5f20\uff0c\u300c\u4f60\u770b\u5979\u7684\u7814\u7a76\uff0c\u5c31\u4f1a\u77e5\u9053\u5979\u5f88\u806a\u660e\u3002<\/P><br \/>\n<P align=left>\u8fd8\u6709\uff0c\u6839\u672c\u5929\u4e0d\u6015\uff0c\u5730\u4e0d\u6015\uff0c\u300d\u4e2d\u7814\u9662\u5206\u5b50\u751f\u7269\u6240\u7814\u7a76\u5458\u859b\u4e00\u82f9\u8bf4\u3002<\/P><br \/>\n<P align=left>\u300c\u6211\u5f88\u5e0c\u671b\u6211\u7684\u7814\u7a76\u53ef\u4ee5\u6551\u4eba\uff0c\u53bb\u6539\u53d8\u4e16\u754c\u3002\u300d\u4e2d\u5174\u5927\u5b66\u517d\u533b\u7cfb\u6bd5\u4e1a\u540e\uff0c\u8521\u7acb\u6167\u5230\u56fd\u5916\u6c42\u5b66\u3002<\/P><br \/>\n<P align=left>\u300c\u76f4\u5230\u770b\u5230\u5f88\u591a\u4e0d\u540c\u7684\u4eba\u540e\uff0c\u6211\u624d\u5f00\u59cb\u60f3\uff0c\u6211\u662f\u600e\u6837\u7684\u4eba\uff0c\u5230\u5e95\u559c\u6b22\u505a\u4ec0\u4e48\uff1f\u300d\u6700\u540e\uff0c\u559c\u6b22\u6df1\u5165\u95ee\u9898\u627e\u7b54\u6848\u7684\u5979\u9009\u62e9\u4e86\u7814\u7a76\u4e4b\u8def\u3002<\/P><br \/>\n<P align=left><B>\u300c\u6211\u5c31\u662f\u96c4\u5fc3\u58ee\u5fd7\uff01\u300d\u4ece\u5206\u5b50\u751f\u7269\u5b66\u5207\u5165\uff0c\u5927\u80c6\u53e6\u8f9f\u8e4a\u5f84<\/B><\/P><br \/>\n<P align=left>\u5f53\u65f6\uff0c\u7855\u58eb\u653b\u8bfb\u5206\u5b50\u751f\u7269\u5b66\uff0c\u535a\u58eb\u653b\u8bfb\u75c5\u6bd2\u5b66\u7684\u5979\uff0c\u4e00\u5f00\u59cb\u4e5f\u662f\u8ddf\u7740\u8001\u5e08\u505a\u764c\u75c7\u7814\u7a76\u3002<\/P><br \/>\n<P align=left>\u800c\u6709\u5173\u764c\u75c7\u7814\u7a76\u7684\u53d1\u73b0\u8d8a\u6765\u8d8a\u591a\uff0c\u53ea\u8981\u7ad9\u5728\u524d\u4eba\u7684\u7814\u7a76\u57fa\u7840\u4e0a\uff0c\u5979\u53ef\u4ee5\u5f88\u5feb\u5c31\u6709\u65b0\u7684\u8fdb\u5c55\u3002<\/P><br \/>\n<P align=left>\u4e0d\u8fc7\uff0c\u5979\u5374\u628a\u773c\u5149\u8f6c\u81f3\u5927\u8111\u795e\u7ecf\u7684\u7814\u7a76\uff0c\u5c24\u5176\u662f\u963f\u5179\u6d77\u9ed8\u75c7\u9886\u57df\uff0c\u300c\u5f53\u65f6\u51e0\u4e4e\u5f88\u591a\u4eba\u90fd\u662f\u505a\u75c5\u7406\u7814\u7a76\uff0c\u300d<\/P><br \/>\n<P align=left>\u4e3b\u8981\u662f\u89c2\u5bdf\u963f\u5179\u6d77\u9ed8\u75c7\u53d1\u751f\u540e\u7684\u5927\u8111\u53d8\u5316\uff0c\u5374\u5c11\u6709\u4eba\u80fd\u89e3\u91ca\u51fa\uff0c\u4e3a\u4f55\u800c\u6765\u3002<\/P><br \/>\n<P align=left>&nbsp;<\/P><br \/>\n<P align=left>\u300c\u5728\u8fd9\u4e2a\u9886\u57df\uff0c\u6709\u592a\u591a\u95ee\u9898\u65e0\u6cd5\u83b7\u5f97\u89e3\u7b54\u3002\u300d\u8521\u7acb\u6167\u60f3\u8981\u4ee5\u5206\u5b50\u751f\u7269\u5b66\u7684\u89d2\u5ea6\u5207\u5165\uff0c\u4ece\u7ec6\u80de\u7684\u53d8\u5316\u5f62\u6210\u53bb\u627e\u51fa\u539f\u56e0\u3002<\/P><br \/>\n<P align=left>&nbsp;<\/P><br \/>\n<P align=left>\u5979\u7684\u5927\u80c6\uff0c\u4ece\u8fd9\u91cc\u770b\u5f97\u51fa\u3002\u5148\u4e0d\u8c08\u5927\u8111\u9886\u57df\u6709\u592a\u591a\u672a\u77e5\u9ed1\u6d1e\uff0c\u5f88\u53ef\u80fd\u7ec8\u5176\u4e00\u751f\u7684\u7814\u7a76\uff0c\u6700\u540e\u90fd\u77f3\u6c89\u5927\u6d77\u3002<\/P><br \/>\n<P align=left>\u5979\u8981\u4ece\u5206\u5b50\u751f\u7269\u5b66\u9886\u57df\uff0c\u8df3\u5230\u5927\u8111\u795e\u7ecf\u9886\u57df\uff0c\u300c\u8fd9\u4ee3\u8868\u4f60\u8981\u975e\u5e38\u5927\u91cf\u7684\u5b66\u4e60\uff0c\u300d\u6c88\u54f2\u9cb2\u8bf4\u3002<\/P><br \/>\n<P align=left>\u4ece\u5927\u8111\u5982\u4f55\u5f62\u6210\u3001\u795e\u7ecf\u5982\u4f55\u53d1\u80b2\u3001\u795e\u7ecf\u7cfb\u7edf\u5982\u4f55\u63a7\u5236\u884c\u4e3a\uff0c\u8fd8\u6709\u5404\u79cd\u5927\u8111\u75be\u75c5\u7684\u75c5\u7406\uff0c\u5bf9\u5979\u800c\u8a00\uff0c\u90fd\u662f\u65b0\u5b66\u95ee\u3002<\/P><br \/>\n<P align=left>\u5373\u4fbf\u5b66\u5b8c\u4e4b\u540e\uff0c\u300c\u4eba\u7c7b\u7ea6\u6709\u4e09\u4e07\u4e8c\u5343\u4e2a\u57fa\u56e0\u6570\uff0c\u6bcf\u4e2a\u57fa\u56e0\u4e5f\u4e0d\u53ea\u4e00\u4e2a\u7ec6\u80de\u5206\u5b50\uff0c\u300d\u4e2d\u7814\u9662\u5206\u751f\u6240\u7814\u7a76\u5458\u7b80\u6b63\u9f0e\u5f62\u5bb9\u3002<\/P><br \/>\n<P align=left>\u5979\u8981\u5206\u8fa8\u51fa\u5f71\u54cd\u963f\u5179\u6d77\u9ed8\u75c7\u7684\u5206\u5b50\uff0c\u5982\u540c\u5927\u6d77\u635e\u9488\u7684\u56f0\u96be\u3002<\/P><br \/>\n<P align=left>\u91cd\u91cd\u5173\u5361\u5728\u5979\u773c\u524d\u3002\u5979\u5374\u8bf4\uff1a\u300c\u8d8a\u96be\uff0c\u8d8a\u6709\u8da3\u300d\u3002<\/P><br \/>\n<P align=left>\u300c\u6211\u6bcf\u5929\u5c31\u662f\u5728\u4e00\u70b9\u4e00\u70b9\u7684\u89e3\u5f00\u7591\u60d1\uff0c\u300d\u8521\u7acb\u6167\u8bf4\u3002\u5f53\u65f6\uff0c\u5979\u53d1\u73b0\u4ee5\u524d\u7814\u7a76\u764c\u75c7\u9886\u57df\u65f6\uff0c\u4e13\u6ce8\u89c2\u5bdf\u7684\u4e00\u4e2a\u540d\u4e3aCDK5 \u7684\u86cb\u767d\u8d28\uff0c<\/P><br \/>\n<P align=left>\u5728\u5927\u8111\u795e\u7ecf\u5143\u53d1\u80b2\u8fc7\u7a0b\uff0c\u626e\u6f14\u5f88\u91cd\u8981\u7684\u89d2\u8272\u3002\u540c\u65f6\uff0c\u53c8\u6709\u4eba\u53d1\u73b0\uff0c\u963f\u5179\u6d77\u9ed8\u75c7\u60a3\u8005\u7684\u5927\u8111\u91cc\u5934\uff0c\u4f3c\u4e4e\u6709\u6bd4\u8f83\u591a\u540d\u4e3aP25 \u7684\u86cb\u767d\u8d28\u3002<\/P><br \/>\n<P align=left>\u8fd9\u4e2d\u95f4\u5230\u5e95\u6709\u6ca1\u6709\u5173\u8fde\u6027\uff1f<\/P><br \/>\n<P align=left>\u300c\u6211\u5c31\u662f\u90fd\u53bb\u8bd5\uff0c\u4e0d\u505c\u7684\u8bd5\uff0c\u300d\u4e00\u4e5d\u4e5d\u4e5d\u5e74\uff0c\u8521\u7acb\u6167\u7814\u7a76\u56e2\u961f\u4e00\u7bc7\u767b\u5728\u300a\u81ea\u7136\u300b\u6742\u5fd7\u4e0a\u7684\u8bba\u6587\uff0c\u9707\u60ca\u5b66\u754c\u3002<\/P><br \/>\n<P align=left>\u5979\u53d1\u73b0\uff0c<B>\u4eba\u7684\u8111\u7ec6\u80de\u91cc\u6709\u4e00\u79cd<\/B><B>P35 <\/B><B>\u86cb\u767d\u8d28\uff0c\u5982\u679c\u5206\u88c2\u6210\u4e3a<\/B><B>P10 <\/B><B>\u4e0e<\/B><B>P25 <\/B><B>\u7684\u86cb\u767d\u8d28\u540e\uff0c<\/B><B>P25 <\/B><B>\u82e5\u5931\u53bb\u63a7\u5236\uff0c\u5c31\u4f1a\u6d3b\u5316\u540d\u4e3a<\/B><B>CDK5 <\/B><B>\u7684\u86cb\u767d\u8d28\u3002<\/B><\/P><br \/>\n<P align=left><B>\u6700\u540e\uff0c\u7ec6\u80de\u9aa8\u67b6\u91cc\u7684\u4e3b\u8981\u6210\u5206<\/B><B>Tau <\/B><B>\u4f1a\u88ab\u78f7\u9178\u5316\uff0c\u9020\u6210\u6211\u4eec\u6240\u770b\u89c1\uff0c\u963f\u5179\u6d77\u9ed8\u75c7\u60a3\u8005\u5927\u8111<\/B><B>X 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align=left>\u4f46\u4e00\u5f00\u59cb\uff0c\u8521\u7acb\u6167\u7684\u53d1\u73b0\uff0c\u5907\u53d7\u6279\u8bc4\u3002\u300c\u5176\u5b83\u79d1\u5b66\u5bb6\u89c9\u5f97\u600e\u4e48\u4f1a\u662f\u4e00\u4e2a\u4ece\u53e6\u4e00\u4e2a\u9886\u57df\u7684\u5e74\u8f7b\u4eba\u505a\u7684\uff0c\u4f1a\u53bb\u8d28\u7591\u7814\u7a76\u8fc7\u7a0b\u7684\u4e25\u8c28\u3002\u300d<\/P><br \/>\n<P align=left>\u300c\u6211\u90a3\u65f6\u4e5f\u65e0\u6cd5\u8c05\u89e3\uff0c\u4ed6\u4eec\u600e\u4e48\u8fd9\u6837\uff08\u8bf4\uff09\uff0c\u300d\u8521\u7acb\u6167\u539f\u672c\u51b7\u9759\u7684\u8bed\u6c14\u5ffd\u7136\u6709\u70b9\u9ad8\u6602\u3002<\/P><br \/>\n<P align=left>\u540e\u6765\u5462\uff1f\u300c\u6211\u89c9\u5f97\u7ed3\u679c\u4f1a\u8bc1\u660e\u4e00\u5207\uff0c\u91cd\u70b9\u662f\uff0c\u6211\u7684\u7814\u7a76\u5bf9\u75c5\u4eba\u6709\u6ca1\u6709\u5e2e\u52a9\uff0c\u6211\u4e0d\u80fd\u53bb\u7ba1\u522b\u4eba\u3002\u300d<\/P><br \/>\n<P align=left>&nbsp;<\/P><br \/>\n<P align=left>\u76f4\u5230\u4e8c\u25cb\u25cb\u56db\u5e74\uff0c\u5176\u5b83\u4eba\u5f00\u59cb\u5927\u91cf\u7814\u7a76\uff0c\u5370\u8bc1\u4e86\u8521\u7acb\u6167\u7684\u8bf4\u6cd5\u3002<\/P><br \/>\n<P align=left>\u4e94\u5e74\u65f6\u95f4\uff0c\u5b64\u5355\u4e2d\uff0c\u8521\u7acb\u6167\u4ecd\u6267\u610f\u524d\u884c\u3002<\/P><br \/>\n<P align=left>&nbsp;<\/P><br \/>\n<P align=left><B>\u300c\u6bcf\u4e00\u5929\u90fd\u5f88\u7d27\u5f20\u300d\u53d1\u73b0\u8bb0\u5fc6\u80fd\u6062\u590d\uff0c\u4f46\u79bb\u9020\u798f\u4e16\u4eba\u8fd8\u5f88\u8fdc<\/B><\/P><br \/>\n<P align=left>&nbsp;<\/P><br \/>\n<P align=left>\u4e8c\u25cb\u25cb\u4e03\u5e74\u4e94\u6708\u3002\u8521\u7acb\u6167\u7684\u7814\u7a76\u56e2\u961f\u5728\u300a\u81ea\u7136\u300b\u53d1\u8868\u4e86\u53e6\u4e00\u4e2a\u53d1\u73b0\u3002<\/P><br \/>\n<P align=left>\u5979\u76f4\u6307\uff0c\u4ece\u52a8\u7269\u7814\u7a76\u4e2d\u53d1\u73b0\uff0c\u60a3\u4e86\u963f\u5179\u6d77\u9ed8\u75c7\u7684\u8001\u9f20\uff0c\u4ecd\u53ef\u80fd\u900f\u8fc7\u73af\u5883\u548c\u836f\u7269\u7684\u523a\u6fc0\uff0c\u627e\u56de\u8bb0\u5fc6\u3002<\/P><br \/>\n<P align=left>&nbsp;<\/P><br \/>\n<P align=left>\u5979\u66ff\u5c0f\u8001\u9f20\u8fdb\u884c\u57fa\u56e0\u6539\u9020\uff0c\u628a\u4f1a\u5f15\u8d77\u963f\u5179\u6d77\u9ed8\u75c7\u7684\u86cb\u767dP25\uff0c\u6539\u4e3a\u53ef\u4ee5\u4eba\u4e3a\u63a7\u5236\u542f\u52a8\u6216\u662f\u5173\u95ed\u3002<\/P><br \/>\n<P align=left>\u7ed3\u679c\u53d1\u73b0\uff0c\u5c0f\u8001\u9f20\u5728P25 \u5173\u95ed\u7684\u65f6\u5019\uff0c\u53ef\u4ee5\u987a\u5229\u907f\u5f00\u7535\u4ee5\u53ca\u901a\u8fc7\u8ff7\u5bab\uff0c\u627e\u5230\u98df\u7269\uff1b\u4e00\u65e6\u542f\u52a8P25 \u4e4b\u540e\uff0c\u5c31\u4f1a\u6162\u6162\u5fd8\u8bb0\u8fd9\u4e9b\u6280\u80fd\u3002<\/P><br \/>\n<P align=left>\u4f46\u662f\uff0c\u5f53\u7814\u7a76\u4eba\u5458\u53bb\u5851\u9020\u4e00\u4e2a\u5feb\u4e50\u7684\u6e38\u620f\u73af\u5883\u7ed9\u5c0f\u8001\u9f20\uff0c\u6216\u8005\u662f\u6295\u5165\u4e00\u79cd\u540d\u4e3aHDAC \u7684\u6291\u5236\u5242\u65f6\uff0c\u539f\u672c\u5931\u53bb\u8bb0\u5fc6\u7684\u5c0f\u8001\u9f20\uff0c<\/P><br \/>\n<P align=left>\u4e0d\u4ec5\u8bb0\u5fc6\u56de\u6765\u4e86\uff0c\u8fd8\u4f1a\u6bd4\u4ee5\u524d\u5b66\u5f97\u66f4\u5feb\u3001\u66f4\u597d\u3002<\/P><br \/>\n<P align=left>&nbsp;<\/P><br \/>\n<P align=left>\u300c\u8fd9\u4ee3\u8868\u4eba\u7684\u8bb0\u5fc6\u6ca1\u6709\u771f\u6b63\u6d88\u5931\uff0c\u53ea\u662f\u8fde\u63a5\u8fd9\u4e9b\u8bb0\u5fc6\u7684\u795e\u7ecf\u4fe1\u9053\u88ab\u963b\u4f4f\u4e86\u3002\u300d<\/P><br \/>\n<P align=left>\u300c\u8fd9\u5c31\u50cf\u957f\u9014\u7535\u8bdd\u7ebf\uff0c\u6709\u65f6\u4f1a\u65ad\u8baf\u6216\u542c\u4e0d\u6e05\u695a\uff0c\u300d\u4f46\u901a\u8def\u4ecd\u5728\uff0c\u53ea\u8981\u6253\u5f00\u5f00\u5173\u3002\u8521\u7acb\u6167\u8ba4\u4e3a\uff0c\u963f\u5179\u6d77\u9ed8\u75c7\u7684\u75c5\u4eba\uff0c\u662f\u53ef\u80fd\u6062\u590d\u7406\u667a\u7684\u3002<\/P><br \/>\n<P align=left>&nbsp;<\/P><br \/>\n<P align=left>\u8521\u7acb\u6167\u4e0d\u77e5\u9053\u8fd9\u4e2a\u7814\u7a76\u7ed3\u679c\u5230\u4e34\u5e8a\u5b9e\u9a8c\uff0c\u6700\u540e\u5316\u4e3a\u836f\u7269\u6765\u6cbb\u7597\u75c5\u4eba\uff0c\u5230\u5e95\u8fd8\u9700\u8981\u591a\u4e45\u65f6\u95f4\u3002<\/P><br \/>\n<P 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